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Pregabalin & Gabapentin

gaba-p, pregabs


Prescription only drug used for treating neuropathic pain and epilepsy and sometimes for treating anxiety.

Pregabalin is more potent than Gabapentin.


method of use

Swallowed. A prescribed dose is usually between 100-300mg a day with a split dose.



Pain relief, drowsiness, relaxed muscles, reduction in anxiety.


health risks

There is a high risk of overdose when Pregabalin or Gabapentin are mixed with other depressants such as alcohol, opiates or benzos.

Pregabalin and Gabapentin both induce tolerance (often called being physically addicted). This means that over time a frequent user will require a higher dosage in order to achieve the same effect.

People often experience serious withdrawal symptoms from these drugs including insomnia, nausea, headache, diarrhoea, sweating, shaking, depression, cravings, panic and irritability. In some reports, the withdrawals have been compared to those of GHB, and are considered almost as bad in severity.

There is a risk of accidents while on these drugs due to their effects on awareness and co-ordination so it’s not advisable to drive or operate machinery.


harm reduction

As mentioned above, don’t mix Pregabalin or Gabapentin with other depressants like alcohol, heroin, methadone or benzos (valium etc.).

Don’t use for extended periods if possible because of the likelihood of dependency.

If you have been using for a while don’t stop suddenly. A medically assisted withdrawal over a week or two is advised.

Don’t inject them – injecting crushed tablets brings many risks and is likely to result in serious injecting injuries.

Be very wary of Pregabalin or Gabapentin bought on the internet or from other people. Many prescription drugs bought online are poor quality and of inconsistent strength.

Published in Alcohol & Drugs